DRAGEN Ultra-Rapid Analysis Pipelines
DRAGEN’s Pipelines are able to achieve NGS data processing speeds orders of magnitude faster than any other methods – without any compromises.
The DRAGEN Genome pipeline enables ultra rapid analysis of Next Generation Sequencing (NGS) data, reducing the time required for analyzing a whole genome at 30x coverage from 10 to 30 hours using the current industry standard, BWA-MEM+GATK-HC software, to ~22 minutes, with the same level of accuracy for both SNPs and INDELs.
DRAGEN’s Joint Genotyping pipeline calls variants from multiple samples at a speed 25x faster than competing pipelines with uncompromising accuracy. The Joint Genotyping pipeline supports pedigree as well as population variant calling from a cohort of samples, and can handle up to ten samples at one time.
Epigenome / Methylation
The Epigenetics is an emerging frontier within sequencing that involves the study of changes in the regulation of gene activity and expression that are independent of gene sequence. The Epigenome Pipeline is an accelerated and more accurate solution for rapidly analyzing methylation data.
The GATK Pipeline is an implementation of GATK Haplotype Variant Caller from the Broad Institute on the DRAGEN Platform. The GATK Pipeline is accelerated by using the API’s of the DRAGEN Bio-IT Processor. The result is a haplotype variant calling pipeline that is able to analyze a 30x coverage whole human genome in 18 minutes. Customers with a valid GATK license from the Broad Institute are able to run GATK on the DRAGEN Platform.