vs. existing software based solutions
DRAGEN is the world’s first next‐generation sequencing (NGS) Bio-IT processor and radically reduces the computational cost and increases the speed without compromising the accuracy of the NGS data analysis pipeline.
The reference‐based mapping, aligning, sorting, deduplication and variant calling that is currently performed by software on extensive cluster or cloud‐based platforms is performed by the DRAGEN processor, which is loaded with highly optimized algorithms for this analysis. DRAGEN can accurately analyze over 50 whole human genomes (from FASTQ to VCF) in less than a day, and reduces the need for clusters of large servers to process the data, lowering costs related to storage space and IT infrastructure.
The DRAGEN Bio‐IT Processor is integrated on a PCIe form-factor card and is provided with accompanying software as a Platform‐as‐a‐Service (PaaS) that can be integrated directly into sequencing instruments and next‐generation sequencing bioinformatics servers.
DRAGEN takes raw read data produced by a sequencing instrument, such as Illumina HiSeq X Ten, in standard FASTQ format (paired‐end or single‐end reads) as an input. DRAGEN’s output, after variant calling, is a standard VCF file ready for tertiary analysis.
Reconfigurable Next-Generation Sequencing Bioinformatics Platform