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DRAGEN Bundled Compute and Storage

Bundled Ultra-Rapid Solution for Clinical Genomics and Research

The DRAGEN Platform and Dell EMC Isilon storage bundle offers a pre-configured, out-of-the-box solution for ultra-rapid analysis and hyper-efficient storage of NGS data.

Key Features

  • Tightly integrated NGS compute and storage in one low footprint appliance
  • DRAGEN ultra-rapid genomic analysis platform and full suite of accelerated pipelines
  • DRAGEN Just-In-Time (JIT) technology compresses a FASTQ and BAM pair by 4x for lossless and by 12x for quantized compression
  • JIT compression/decompression happens just-in-time and in near real-time
  • JIT compression technology drives a dramatic decrease in ongoing storage costs
  • Slimline 1U Dell C4130 server with DRAGEN FPGA Accelerator Card
  • Best-in-class DELL EMC Isilon scale-out NAS storage
  • Preconfigured and tested for optimum performance
  • Includes installation and two years support and maintenance
  • Simple to order – fast delivery

Fast Analysis – Fast Storage

Increasing analytics performance is one part of the equation; providing and absorbing the tremendous amounts of data consumed and generated is another. The Edico-Dell EMC joint solution provides the performance, scalability, and functionality required by the Edico-accelerated workflow. Dell EMC Isilon Scale-Out NAS provides a highly available and reliable file system for Life Sciences applications and workflows. Isilon’s storage architecture automatically aligns application needs with performance, capacity, and economics. As performance and capacity demands increase, both can be scaled simply and non-disruptively, allowing sequencing applications and users to continue working.

The Isilon single volume storage solution consolidates large, semi-structured file-based data workflows into a single system that supports Edico’s multiple DRAGEN pipeline workflows. DRAGEN’s variety of input formats and industry standard output formats are supported by Isilon’s single storage system simplifies integration, and is transparent to users. Isilon’s interface flexibility is supported by multiple protocols, such as SMB, NFS, Swift, and HDFS to support a wide variety of genomics technologies, user access methods, and analysis environments.

Bundled Compute and Storage

Essentials

  • FAST: DRAGEN™ able to achieve NGS data processing speeds orders of magnitude faster than any other methods – without any compromises

  • ACCURATE: DRAGEN™ produces the highest possible accuracy for clinical interpretation and treatment guidance

  • FLEXIBLE: The reconfigurable DRAGEN™ Bio-IT Platform can be loaded with highly optimized algorithms for many different NGS secondary analysis pipelines—such as Whole Genome or Exome, RNAseq, Methylome, Microbiome and Cancer

  • COST-EFFECTIVE: DRAGEN™ reduces the need for clusters of larger servers, significantly lowering costs related to storage space and IT infrastructure.

DRAGEN and Isilon for NGS Data Analysis and Storage

Edico Genome and Dell EMC have collaborated to offer a bundled compute and storage solution for rapid, cost-effective and accurate analysis of Next Generation Sequencing (NGS) data. The highly optimized solution includes the Edico Genome DRAGEN™ Bio-IT Platform integrated within a 1U Dell 4130 server paired with Dell EMC Isilon scale-out networked attached storage (NAS) for ultra-efficient genomic data storage. Leveraging Isilon and DRAGEN together provides faster time-to-insights, cost savings, and the flexibility and protection of enterprise storage capabilities.

The bundled solution enables analysis of a whole human 30x genome in as little as 22 minutes, which can typically take over a day using standard software. DRAGEN can accurately analyze over 50 whole human genomes (from FASTQ to VCF) in less than a day, and reduces the need for clusters of large servers to process the data, lowering costs related to storage space and IT infrastructure. Further, managing the tremendous amounts of NGS data consumed and generated is a challenge. Dell EMC Isilon  scale-out NAS provides the performance, scalability, and reliability for data-intensive Healthcare-Life Sciences applications and workflows.

DRAGEN Just-In-Time Compression Technology

Edico Genome’s FPGA-enabled compression technology is designed to reduce the storage footprint of NGS data by shrinking the amount of genomic information stored for a FASTQ and BAM pair by 4x for lossless and by 12x for quantized compression, driving a dramatic decrease in ongoing storage costs. Get the most out of your Isilon storage system with DRAGEN JIT Compression – greatly reduced storage footprint with the same user experience of keeping all your data in an uncompressed format. Compression/decompression happens just-in-time and in near real-time.

DRAGEN EMC Isilon

Reliable & Versatile Storage Architecture

Dell EMC Isilon is a proven scale-out Network Attached Storage (NAS) solution that can handle the unstructured data prevalent in end-to-end NGS workflows. Isilon can be used as a central storage system that accepts output from NGS instruments, acts as primary data storage for a compute cluster, and provides deep capacity for data archiving.

Isilon supports multiple protocols, such as SMB, NFS, Swift and HDFS, across a wide variety of genomics technologies, user access methods and analysis environments. An Isilon storage cluster consolidates large, unstructured file based data such as FASTQ, BAM and VCF files into a single system that simplifies solution integration, and is transparent to users.

The Isilon storage cluster provides the versatility needed in life sciences and healthcare IT environments. The Isilon storage architecture automatically aligns application needs with performance, capacity, and economics. As performance and capacity demands increase, both can be scaled simply and non-disruptively by adding another performance or capacity storage node.

Dell EMC Isilon

Dell PowerEdge C4130

Analysis Results in Minutes, Not Hours

The PowerEdge C4130 is an incredibly dense rack server designed to accelerate a range of demanding workloads including genomics. With up to two DRAGEN FPGA accelerators in just 1U of space, the C4130 delivers outstanding performance, flexibility and efficiency while reducing your space, cost and management requirements.

Match your unique workload requirements with a balanced architecture offering a flexible combination of accelerator, processor, memory and I/O options:

  • Scalable performance with the latest Intel® Xeon® processor
  • I/O flexibility with support for InfiniBand FDR

PowerEdge Server

Dell EMC Enables Life Sciences Workflows

Dell EMC is a global leader and trusted partner in Life Science solutions. We deliver powerful yet versatile compute and storage products for healthcare and life science organizations that want to efficiently manage clinical and genomics data. Dell EMC solutions are simple to install, manage and scale, at any size, across the R&D data life-cycle. Dell EMC actively participates in industry organizations such as the Global Alliance For Genomics and Healthcare (GA4GH) and the IRODS Consortium with an aim eliminate the complexities of storage so life scientists can focus on research.